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2 425 867

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IPC

C12N1/20(2006-01-01)

C12R1/63(2006-01-01)

A61K39/106(2006-01-01)

(21) (22)

Application

2010131327/10, 2010-07-26

(24)

Start date

2010-07-26

(22)

Actual filing date

2010-07-26

(45)

Published

2011-08-10

(72)

Inventor

Livanova Ljudmila FedorovnaStrel'Nikova-Aab Ekaterina NikolaevnaZadnova Svetlana PetrovnaSmirnova Nina Ivanovna

(73)

Holder

Federal'Noe Gosudarstvennoe Uchrezhdenie Zdravookhranenija Nauchno-Issledovatel'Skij Protivochumnyj Institut Federal'Noj Sluzhby Po Nadzoru V Sfere Zashchity Prav Potrebitelej I Blagopoluchija Cheloveka

AVIRULENT STRAIN OF Vibrio cholerae KM 263 BACTERIA OF SEROVAR INABA OF BIOVAR ELTOR - PRODUCER OF PROTECTIVE O1 ANTIGEN Russian patent published in 2011 - IPC C12N1/20 C12R1/63 A61K39/106

Abstract RU 2425867 C1

FIELD: medicine.

SUBSTANCE: avirulent Vibrio cholerae KM 263 strain of biovar eltor of serovar Inaba - a producer of a protective O1 antigen is produced in a simulation experiment of virulent natural V.cholerae M569 Inaba strain by spontaneous loss of "СТХφ" prophage at cholera agent continuance in sterile river water. The strain is characterised by a high production level of the major protective O1 antigen of serovar Inaba.

EFFECT: invention aims at preparing chemical cholera vaccines by formation of antibacterial cholera immunity, and producing purified preparation of the O1 antigen of serovar Inaba for a diagnostic serum preparation .

5 ex

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RU 2 425 867 C1

Authors

Livanova Ljudmila Fedorovna

Strel'Nikova-Aab Ekaterina Nikolaevna

Zadnova Svetlana Petrovna

Smirnova Nina Ivanovna

Dates

2011-08-10—Published

2010-07-26—Filed