METHOD OF OPTICAL ANALYSIS OF THROMBOCYTE AGGREGATION Russian patent published in 2011 - IPC G01N33/49 

FIELD: medicine.

SUBSTANCE: for thrombocyte aggregation analysis, a blood sample is mixed by periodic absorption of a sample portion from a container into a capillary to be thereafter displaced to the container back. An electric signal is transformed into light beam intensity passed through a segment of the capillary found in a measuring channel and relevant to double crossing of said segment by a meniscus during each aspiration and displacement cycle in the electric signal. The pulses formed by crossing of the light beam by the sample during each aspiration and displacement cycle are isolated. An average value of the amplitude U_c of each pulse is related to a component level of the electric signal preceding its rise-up portion; its root mean square deviation σ is calculated, while the mean size of thrombocyte aggregates is shown by the squared relation σ/U_c.

EFFECT: more uniform mixing of small volume of the blood samples and eliminated action of optical transmission of the capillary walls and light beam instability on the measurement results.

4 cl, 6 dwg