METHOD OF CONSERVATIVE TREATMENT OF WOMEN IN PREMENOPAUSE PERIOD WITH PROLAPSE OF GENITALIA Russian patent published in 2011 - IPC A61K31/375 A61K31/56 A61K33/06 A61K38/43 A61P15/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to gynecology and can be used for conservative treatment of women in premenopause period with prolapse of genitalia. In women in premenopause period with prolapse of genitalia, undergoing substituting hormonal therapy, level of C-end telopeptides is determined, if values are lower than 0.6 ng/ml, only substituting hormonal therapy is administered. If values equal and are higher than 0.6 ng/ml, additionally to substituting hormonal therapy administered is metabolic therapy in form of ascorbic acid in dose 500 mg 3 times per day and magnerot in dose 500 mg 3 times per day for three months. Additionally determined is amount of immunoglobulin E, circulating immune complexes, C3- and C4-components of complement. If level of immunoglobulin E is higher than 150 IU/ml, circulating immune complexes more than 200 units of optic density, C3-component of complement lower and equal 83 mg/dl, C4-component of complement lower and equal 18 mg/dl, to substituting hormonal and metabolic therapy additionally administered is vobenzim in dose 3 pills 3 times per day for three months.

EFFECT: method provides specified differentiated approach to selection of treatment method and determination of specific schemes of treatment depending on connective tissue state, as well as taking into account immune status, makes it possible to normalise disturbed with connective tissue pathology collagen metabolism, prevent development of genitalia prolapse in combination with connective tissue dysplasia and 2 times reduce degree of said disease progressing.

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