METHOD OF DIFFERENTIAL DIAGNOSTICS OF PRIMARY OPEN-ANGLE GLAUCOMA IN PATIENTS WITH PROGRESSING MYOPIA Russian patent published in 2011 - IPC A61B3/10 

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, in particular to ophthalmology, and can be used for diagnostics of clinical version of primary open-angle glaucoma (POAG) in patients with progressing myopia. In patients with progressing myopia by method of transcranial duplex scanning initial value of maximal systolic rate of blood flow (V_{max 0}) in medial cerebral artery (MCA) is determined. After that hypercapnia test is performed and value of maximal systolic rate of blood flow in MCA is determined after hypercapnia test (Vmaxi).15-20 minutes later hypercapnic test is performed and value of maximal systolic rate of blood flow in MCA is determined after hypercapnia test (V_{max 2}). After carrying out tests by formulas calculated are increase of V_{max 1} and reduction of V_{max 2}, %

where δ V_{max 1} is increase of V_{max 1} in MCA, %, δ V_{max 2} is reduction of V_{max 2} in MCA, %. After that day monitoring of arterial pressure is performed and determined are values of average day systolic (SAP_aver) and diastolic (DAP _aver) pressure, variability of systolic arterial pressure during day (VSAP_d) and night (VSAP_n), variability of diastolic arterial pressure during day (VDAP_d) and night (VDAP_n). If value of δ ,V_max1>30%, SAP_aver≤ 105.0 mm Hg, DAP_aver ≤ 70.0 mm Hg, VSAP_d ≥ 10.0 mm Hg VDAP_n ≥ 9.0 mm Hg, discircular version of POAG is diagnosed; if value of δ V_{max 2}>30%, SAP_aver≥ 115.0 mm Hg, DAP _aver ≥ 75.0 mm Hg, VSAP_d≤ 10.0 mm Hg, VDAP_n ≤ 9.0 mm Hg, ischemic version of POAG is diagnosed.

EFFECT: method makes it possible to perform differential diagnostics of clinic versions of POAG in patients with progressing myopia at early stages of disease with high degree of accuracy.

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