METHODS OF APPLYING (+)-1,4-DIHYDRO-7-[(3S,4S)-3-METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OXO-1-(2-THUASOLYL)-1,8-NAPHTHYDIRINE-3-CARBOXYLIC ACID FOR TREATMENT OF CANCER Russian patent published in 2011 - IPC A61K31/4375 A61P35/00 

Abstract RU 2428983 C2

FIELD: medicine.

SUBSTANCE: methods in accordance with invention relate to introduction of enantiomerically pure (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methyamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiasolyl)-1,8-naphthydirine-3-carboxylic acid in dose from 50 to 90 mg/m2 for treatment of myelogenous leukemia leukemia and in dose from 45 to 75 mg/m2 for treatment of ovary cancer.

EFFECT: extension of arsenal of medications for treatment of ovary cancer and myelogenous leukemia.

37 cl, 15 tbl, 20 dwg, 11 ex

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RU 2 428 983 C2

Authors

Ehjdelman Dehniel S.

Silverman Dzheffri A.

Arkin Majkl

Khajd Dzhennifer

Uolker Dunkan

Rajt Zhasmin

Dates

2011-09-20Published

2006-09-05Filed