COMBINATION OF APO2L/TRAIL AND EGFR INHIBITOR FOR CANCER TREATMENT, METHOD IN VITRO OF APOPTOSIS INCREASE AND APPLICATION OF COMBINATION FOR OBTAINING MEDICATION FOR CANCER TREATMENT Russian patent published in 2011 - IPC A61K38/17 A61K31/517 A61K39/395 C07K14/525 C07K14/47 C07K14/705 

Abstract RU 2429006 C2

FIELD: medicine.

SUBSTANCE: in order to increase apoptosis in mammalian cells, combination, containing efficient amount of polypeptide Apo2L/TRAIL and EGFR inhibitor, representing N-(3-ethinylphenyl)-6,7-bis(2-methoxyetoxy)-4-chinasolinamine is used.

EFFECT: invention makes it possible to use combination efficiently to increase apoptosis, in which sinergetic activity of claimed composition is demonstrated.

15 cl, 12 dwg, 7 ex

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RU 2 429 006 C2

Authors

Ashkenazi Avi Dzh.

Dates

2011-09-20Published

2006-02-16Filed