FIELD: chemistry.
SUBSTANCE: method is realised by reacting 2-n-propyl-4-methyl-6-(1'-methylbenzimidazol-2'-yl)benzimidazole with a compound of formula
, in which Z denotes a leaving group. The compound obtained this way undergoes suitable treatment if necessary. The cyano group of the obtained 2-cyano-4'-[2"-n-propyl-4"-methyl-6"-(1'"-methylbenzimidazol-2'"-yl)benzimidazol-1"-ylmethyl]biphenyl of formula
is then converted to an acid functional group through hydrolysis at temperature ranging from 140°C to 200°C in the presence of a base in a system of high-boiling solvents, and the obtained telmisartan is converted to a hydrochloride during processing if necessary.
EFFECT: easy processing, treatment and extraction of telmisartan.
12 cl, 7 ex
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