FIELD: medicine.
SUBSTANCE: described are novel versions of erythropetine (EPO), representing deleted forms of hormone, which possess cytoprotective, in particular, neuroprotective, function, without, in fact, demonstrating hemopeotic activity, as well as their obtaining by method of recombinant DNAs and means requited for its realisation (vector constructions and host-cells).
EFFECT: claimed is application of novel EPO versions with cytoprotective action as active agent in manufacturing medicines for treatment or prevention of state, associated with tissue damage induced by cell death.
22 cl, 30 dwg, 1 ex
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