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(19)

RU

(11)

2 490 276

(13)

C2

(51)

IPC

C07K16/24(2006-01-01)

A61K39/395(2006-01-01)

A61P37/00(2006-01-01)

(21) (22)

Application

2008118227/10, 2003-01-21

(24)

Start date

2003-01-21

(22)

Actual filing date

2003-01-21

(45)

Published

2013-08-20

(72)

Inventor

Spresher Sindi A.Kejper Jozef L.Dasovich Marija M.Grant Frehnsis Dzh.Khehmmond Andzhela K.Novak Dzhulija E.Gross Dzhejn A.Dillon Stejsi R.

(73)

Holder

Zajmodzhinetiks, Ink.

NEW LIGAND OF CYTOKINE RECEPTOR ZCYTOR17 Russian patent published in 2013 - IPC C07K16/24 A61K39/395 A61P37/00 

Abstract RU 2490276 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to biotechnology. What is presented is a method of treating a mammal suffering an inflammatory disease wherein the inflammatory disease is atopic dermatitis, eczema, or itch. The method comprises administering to a mammal a recovered monoclonal antibody or antigen-binding fragment thereof which is prepared by inoculating a non-human animal an adjuvant and a polypeptide (zcytor17lig) containing amino acid residues 27-164 SEQ ID NO: 2, followed by recovering said antibodies from said animal.

EFFECT: using the invention can find application in medicine for treating atopic dermatitis, eczema, or itch.

2 cl, 7 dwg, 21 tbl

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RU 2 490 276 C2

Authors

Spresher Sindi A.

Kejper Jozef L.

Dasovich Marija M.

Grant Frehnsis Dzh.

Khehmmond Andzhela K.

Novak Dzhulija E.

Gross Dzhejn A.

Dillon Stejsi R.

Dates

2013-08-20—Published

2003-01-21—Filed

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