METHOD FOR MAKING MAGNETITE NANOPARTICLES STABILISED BY BIOCOMPATIBLE POLYMER HAVING FUNCTIONAL FORMYL GROUPS Russian patent published in 2011 - IPC A61K9/16 A61K47/02 C01G49/08 B82B3/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention can be used for creation of magnetic-susceptible sorbents applicable in medicine. A method for making magnetite nanoparticles stabilised by a biocompatible polymer having available functional formyl groups, involves preparation of magnetite of two mixed salts of ferrous iron and ferric iron adsorbed in polymeric matrixes, and modification of end groups of polymer. Magnetite is produced by coprecipitation in an alkaline medium of two mixed salts of ferrous iron and ferric iron, and at least one polymer selected from a number: chitosan, polyvinyl alcohol, block copolymer of polystyrene and polyethylene oxide. The weight relation of polymers in the composite makes 4 to 46 wt %. The produced composite is dispersed, processed in an aqueous solution of glutaraldehyde and washed. All the operations are combined with continuous ultrasound exposure.

EFFECT: invention allows producing multiuseable steady magnetite nanoparticles.

3 cl, 2 dwg, 1 tbl, 5 ex