METHOD OF PHOTODYNAMIC THERAPY AND SURGICAL ABLATION OF INTRAOCULAR NEOPLASM Russian patent published in 2011 - IPC A61F9/00 A61N5/67 A61B17/00 A61K31/409 A61P35/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine and can be used for photpdynamic therapy and surgical ablation of intraocular neoplasm. For this purpose, photosensitiser of chlorine series is introduced to patient intravenously in dose 0.8-1.1 mg/kg × 0.7 2 hours before irradiation. 10 minutes before irradiation the same photosensitiser is introduced to patient intravenously in bolus manner in dose 0.8-1.1 mg/kg × 0.3. Before second introduction of photosensitiser above tumour formed is superficial scleral flap with base from limb and thickness equal to 2/3 of sclera thickness. 10 minutes after second introduction of photosensitiser scleral bed is irradiated by means of lightconductor nozzle by laser irradiation with energy density 300 J/cm² covering neighbouring fields on 5% of area. After finishing irradiation tumour is ablated transsclerally. After that gas SF6 is introduced intravitreally until normal tonus is achieved. After that by means of lightconductor nozzle laser irradiation around scleral flap is performed with energy density 100 J/cm² covering covering neighbouring fields on 5% of area.

EFFECT: method makes it possible to ensure photoinduced thrombosis of neoplasm-feeding vessels, death of tumour cells, complete ablation of tumour, achieve absence of recurrences and metastases in remote postoperative period.

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