FIELD: medicine, pharmaceutics.
SUBSTANCE: inventions relate to methods of obtaining therapeutically effective medication for treatment and/or improvement of condition in case of disseminated intravascular clotting (DIC), methods of treatment and/or improvement of conditions in case of DIC of patients in whose plasma activity of antithombin constitutes 40% or less. Essence of invention consists in the fact that applied is thrombomodulin obtained by transfection of cells-hosts by means of DNA, which codes amino-acid sequence SEQ ID NO: 9 or 11.
EFFECT: improvement of condition in case of disseminated intravascular clotting.
10 cl, 1 tbl
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