FIELD: pharmacology.
SUBSTANCE: isolated antibody molecule, specifically binding to the thrombin exosite area 1, and an antigen-binding fragment of said antibody, are provided. The use of the antibody molecule in the manufacture of medicaments is considered. A pharmaceutical composition is described as well as a method for treating a thrombin-mediated condition.
EFFECT: use in the treatment of diseases associated with thrombin.
25 cl, 22 dwg, 4 tbl
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