N-(4-FLUOROBENZYL)-N-(1-METHYLPIPERIDIN-4-YL)-N'-(2-METHYLPROPYLOXY)PHENYLMETHYL) CARBAMIDE SALTS AND PREPARATION OF SAID SALTS Russian patent published in 2010 - IPC C07D211/58 A61K31/4468 A61P25/00 A61P7/02 

Abstract RU 2387643 C2

FIELD: chemistry.

SUBSTANCE: invention relates to novel N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide salts of formula I , containing an anion selected from a group consisting of phosphate, sulphate, succinate, malate, citrate, fumarate, maleate and edisilate. The invention also relates to a method for synthesis of salts in paragraph 1, to a pharmaceutical composition, a method of inhibiting monoamine receptor activity, as well as to use of at least one salt in paragraph 1.

EFFECT: obtaining novel biologically active compounds which are active as inhibitors or inverse agonists of the monoamine receptor.

50 cl, 9 ex, 9 tbl

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RU 2 387 643 C2

Authors

Tjugesen Mikkel'

Shlinger Natali

Tol'F Bo-Ragnar

Blatter Fritts

Bergkhauzen Jorg

Dates

2010-04-27Published

2005-09-26Filed