THERAPEUTIC AGENT AND DIAGNOSTIC AGENT FOR CEREBRAL DISEASES OF CAUSED BY MITOCHONDRIAL DYSFUNCTION Russian patent published in 2011 - IPC A61K33/16 A61K31/197 A61K49/00 A61P9/10 A61P25/06 A61P25/16 A61P25/28 A61P25/00 

FIELD: medicine.

SUBSTANCE: invention refers to a therapeutic and diagnostic agent used in treatment or diagnostics of a cerebral disease caused by a mitochondrial dysfunction, or in a method for prevention within a surgical intervention and an intravascular surgery, and also to a diagnostic technique for cerebral diseases. The therapeutic agent contains an iron compound and δ-aminolevulinic acid or its salt by formula R²R¹NCH₂COCH₂CH₂COR³ (1) where each R¹ and R² independently represents hydrogen atom, and R³ represents a hydroxyl group or C_1-24 alkoxy group. The diagnostic agent contains 8-aminolevulinic acid or its salt by formula specified above. The diagnostic technique for the cerebral disease caused by mitochondrial dysfunction, involves a stage of introduction of the specified diagnostic agent followed by a stage of exposure of a diagnosed brain region to light, capable to excite protoporphyrin IX, accompanied by emission of red light, and a stage of diagnostics of the involved brain by the detected emission of red light.

EFFECT: higher diagnostic efficiency.

7 cl, 4 dwg, 2 ex