FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions refers to medicine and pharmacology. An agent for treating and preventing diseases associated with stress-related conditions in diseases and disorders in human and animals represents nonapeptide KND by formula as follows: Trp-Lys-Gly-Gly-Asn-Ala-Ser-Gly-Glu, or nonapeptide Trp-Lys-Gly-Gly-Asp-Ala-Ser-Gly-Glu or hexapeptide Trp-Lys-Gly-Gly-Asn-Ala or their pharmaceutically acceptable salts. A pharmaceutical composition for treating and preventing the diseases associated with stress-related conditions in diseases and disorders in human and animals contains nonapeptide KND or nonapeptide Trp-Lys-Gly-Gly-Asp-Ala-Ser-Gly-Glu or hexapeptide Trp-Lys-Gly-Gly-Asn-Ala and glycin and/or a natural antioxidant, particularly, carnosine or homocarnosine. The ingredients of the pharmaceutical composition are related as follows: nonapeptide or hexapeptide: glycin:natural antioxidant makes 1:(10-125):(10-125) by weight. The pharmaceutical composition is used in the form of nasal drops, in the form of spray, powder spray, aerosol, sublingually in the form of lozenge, capsules and powders, in the form of various injections, in the form of suppositories, ointments, creams, lotions. A method of treating and preventing the diseases associated with stress-related conditions in diseases and disorders in human and animals consists in introducing in an organism said pharmaceutical composition 10 mcg/kg to 10 mg/kg at nonapeptide KND or nonapeptide Trp-Lys-Gly-Gly-Asp-Ala-Ser-Gly-Glu or hexapeptide Trp-Lys-Gly-Gly-Asn-Ala.
EFFECT: invention provides higher clinical and preventive effectiveness in the diseases associated with stress-related conditions in diseases and disorders in human and animals.
6 cl, 5 tbl
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