METHOD OF DETERMINATION OF ETHANOL AND OTHER METABOLITES CONTENT IN HUMAN BLOOD Russian patent published in 2011 - IPC G01N33/48 G01N30/02 

Abstract RU 2436088 C2

FIELD: medicine.

SUBSTANCE: invention describes a method of determination of ethanol and other metabolites content in human blood by liquid phase chromatography, including preparation of blood distillates by vapour straight distillation and blood component analyis, characterised by the fact that it is combined with one-stage quantitative determination of ethanol, diethyl ester, acetaldehyde, acetone, methylacetate, ethylacetate, propyl alcohol, isobutyl alcohol, butyl alcohol, isoamyl alcohol with the use of capillary chromatographic columns; the concentration of the determined blood components is calculated by formula: where a is chromatographic study results, mg/dm3; V is a distillate volume, cm3; m is a whole blood weight, g.

EFFECT: method can be used in clinical laboratory diagnostics in studies of metabolic disorders caused by alcohol poisoning, and in judicial medical activity for diagnosing of a degree of intoxication of live persons.

1 ex, 1 tbl, 2 dwg

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RU 2 436 088 C2

Authors

Postnova Tat'Jana Vjacheslavovna

Stepanova Irina Petrovna

Patjukov Aleksandr Georgievich

Vysokogorskij Valerij Evgen'Evich

Dates

2011-12-10Published

2009-12-25Filed