METHOD OF CONTENT CHANGE OF LIPID PEROXIDATION PRODUCTS: DIENE CONJUGATES, HYDROPEROXIDES IN COMMON LIPIDS OF LIVER, LUNG, MYOCARDIUM, BLOOD, MALONDIALDEHYDE IN AQUEOUS PHASE OF LIVER, MYOCARDIUM, LUNG, BLOOD HOMOGENATE CAUSED BY SIMULTANEOUS OR SELECTIVE EXCITATION OF PERIPHERAL MUSCARINE-SENSITIVE, NICOTINE-SENSITIVE CHOLINOCEPTIVE STRUCTURES OF PLASMATIC CELL MEMBRANE WITH USING ANTICHOLINESTERASE MECHANISMS OF ENDOGENOUS ACETYLCHOLINE ACCUMULATION IN COLD LOADINGS IN EXPERIMENT Russian patent published in 2011 - IPC G09B23/28 

FIELD: medicine.

SUBSTANCE: for content change of lipid peroxidation products in laboratory rats caused by simultaneous or selective excitation of peripheral muscarine-sensitive and nicotine-sensitive structures (M- and N-cholinoceptive structures) of a plasmatic cell membrane, anticholinesterase accumulation mechanisms of endogenous acetylcholine in tissues are used. 30 minutes prior to the introduction of proserin, the rats are prescribed with: benzohexonium for activation of M-cholinoceptive structures only; methacin and atropine for activation of N-cholinoceptive structures only; proserin only is required for simultaneous excitation of peripheric M- and N-cholinoceptive structures. The experimental animals are placed in an environmental camera for cooling.

EFFECT: method allows changing the content of lipid peroxidation products in laboratory rats caused by simultaneous or selective excitation of peripheral M- and N-cholinoceptive structures of the plasmatic cell membrane with using anticholinesterase accumulation mechanisms of endogenous acetylcholine in tissues in the cold-loaded environment.

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