FIELD: medicine.
SUBSTANCE: invention relates to field of veterinary. Essence of method of determination of sensitising properties of atypical microbacteria lies in carrying out allergic research of live stock. Separation of atypical microbacteria from biomaterial and determination of their sensitising properties on guinea pigs are realised by hypodermic infection with separated culture. Atypical cultures are introduced fractionally, trice, by equal parts after 24 hours in dose 20 mg/head with the following hypodermic introduction on 30-th day of only tuberculin-PPD. In case if after 48 hours allergic reaction, hyperemia, increase of over 5 mm of tissues volume and ulcers in place of introduction, as well as hyperplasia of regional lymph nodes are presents, sensitising properties of atypical microbacteria are determined.
EFFECT: application of claimed method makes it possible to increase efficiency of determination of sensitising properties of atypical microbactriua.
4 ex, 4 tbl
| Title | Year | Author | Number |
|---|---|---|---|
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|
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