HETERODIMERIC POLIPEPTIDES IL-17 A/F AND POSSIBILITIES OF THEIR THERAPEUTIC APPLICATION Russian patent published in 2012 - IPC A61K38/20 C07K14/54 C07K16/24 

Abstract RU 2440134 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions relates to medicine, namely to immunology, and can be used for treatment of immune-mediated disease in mammal which needs it. For this purpose efficient amount of one or more antagonists capable of inhibiting both IL-17A (SEQ ID NO: 3), and IL-17F (SEQ ID NO: 4) in polypeptide IL-17A/F is introduced.

EFFECT: inventions ensure higher efficiency of treatment of immune-mediated diseases, due to novel polypeptide of interleukin17 (IL-17) family.

25 cl, 20 dwg, 9 tbl, 15 ex

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RU 2 440 134 C2

Authors

Gerni Ostin L.

Balazh Mersedes

Gilardi Niko

Khajmovitts Sara

Khass Filip E.

Starovasnik Melissa A.

Vu Jan'

Li Dzhejms M.

Ehrnott Dehvid P.

Oujan Vehn'Tszjun'

Dates

2012-01-20Published

2007-11-20Filed