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(19)

RU

(11)

2 440 349

(13)

C2

(51)

IPC

C07D401/04(2006-01-01)

C07D401/12(2006-01-01)

C07D401/14(2006-01-01)

C07D403/04(2006-01-01)

C07D403/12(2006-01-01)

C07D405/12(2006-01-01)

C07D239/42(2006-01-01)

C07D413/12(2006-01-01)

C07D417/12(2006-01-01)

A61K31/506(2006-01-01)

A61K31/5377(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2009110255/04, 2007-08-21

(24)

Start date

2007-08-21

(22)

Actual filing date

2007-08-21

(45)

Published

2012-01-20

(72)

Inventor

Finlej Moris Rajmond VerskojlMorris DzheffriPajk Kurt Gordon

(73)

Holder

Astrazeneka Ab

MORPHOLINOPYRIMIDINE DERIVATIVES USEFUL FOR TREATING PROLIFERATIVE DISORDERS Russian patent published in 2012 - IPC C07D401/04 C07D401/12 C07D401/14 C07D403/04 C07D403/12 C07D405/12 C07D239/42 C07D413/12 C07D417/12 A61K31/506 A61K31/5377 A61P35/00 

Abstract RU 2440349 C2

FIELD: chemistry.

SUBSTANCE: invention relates to compounds of formula or pharmaceutically acceptable salt thereof, synthesis methods thereof, pharmaceutical compositions containing said compounds, and use thereof to prepare a medicinal agent having mTOR kinase and/or PI3K kinase inhibiting action.

EFFECT: improved properties of the derivatives.

15 cl, 72 ex

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RU 2 440 349 C2

Authors

Finlej Moris Rajmond Verskojl

Morris Dzheffri

Pajk Kurt Gordon

Dates

2012-01-20—Published

2007-08-21—Filed

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