METHOD FOR BLOOD PURIFICATION FROM DNA-CONTAINING IMMUNE COMPLEXES USING COMBINED SORBENT Russian patent published in 2012 - IPC A61M1/38 A61K38/43 A61K38/17 A61P37/00 

FIELD: medicine.

SUBSTANCE: invention is referred to the area of medicine, namely rheumatology, immunology and biotechnology and is related to lowering of content of DNA-containing circulating immune complexes in blood. In order to do that the blood is filtered through the original combined sorbent which is a composition consisting of granulated drug with immobilized DNAse I and granulated drug with immobilized Clq-component of complement. Both drugs are being synthesized separately using the emulsion polymerization method in the gaseous nitrogen flow on the basis of polyacrylamide carrier with magnetic properties which is granulated at the 2:1 carrier: iron ratio.

EFFECT: method provides for significant decrease of release of duplex DNA antibodies that are released into the blood flow in process of destruction of DNA-containing circulating immune complexes, while maintaining the effectiveness of destruction of said complexes.

1 dwg, 2 ex, 2 tbl