METHOD OF SIMULTANEOUS REMOVAL OF INTERLEUKIN-12 AND INTERLEUKIN-23 FROM BIOLOGICAL FLUIDS USING MAGNETICALLY CONTROLLED GRANULES Russian patent published in 2018 - IPC A61M1/34 

Abstract RU 2670674 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to immunology and biotechnology. Blood is passed through a granular preparation with immobilized concentrated monoclonal antibodies to interleukin-12 and interleukin-23. At the same time, for the immobilization of antibodies to IL-12 and IL-23, a polyacrylamide carrier with magnetic properties is used at a ratio of the carrier : iron 2:1, which is granulated by emulsion polymerization.

EFFECT: method allows to provide a more expressed decrease in concentration of cytokines in the perfusion blood without changing the content of the formed elements of the blood, makes it possible to reuse the used granules.

1 cl, 3 ex, 3 tbl

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RU 2 670 674 C1

Authors

Gontar Ilya Petrovich

Emelyanova Olga Ivanovna

Rusanova Olga Aleksandrovna

Maslakova Larisa Aleksandrovna

Zborovskaya Irina Aleksandrovna

Dates

2018-10-24Published

2017-05-02Filed