METHOD FOR PREPARING PREPARATION FOR RHEUMATOID FACTOR REMOVAL FROM BLOOD OF PATIENTS WITH RHEUMATOID ARTHRITIS Russian patent published in 2020 - IPC A61K39/395 A61K9/14 

Abstract RU 2739352 C1

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention refers to pharmaceutics, namely to a method for preparing a preparation for removing rheumatoid factor from blood of patients suffering rheumatoid arthritis. Method comprises passing blood through a sorbent, which is polyacrylamide iron-containing granules, in which as a result of emulsion polymerisation immobilized Fc-fragment immunoglobulin G, obtained during papain hydrolysis and purification of native human immunoglobulin G.

EFFECT: invention provides higher sorption and specific capacity of the preparation for removal of rheumatoid factor from blood by separation of human immunoglobulin IgG into fragments Fc and Fab and further operation only with fraction containing Fc fragment.

1 cl, 3 tbl, 3 ex

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RU 2 739 352 C1

Authors

Gontar Ilya Petrovich

Emelyanova Olga Ivanovna

Rusanova Olga Aleksandrovna

Zborovskaya Irina Aleksandrovna

Dates

2020-12-23Published

2020-03-23Filed