FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to chemical-pharmaceutical industry. A medication is prepared at the following stages (i) and (ii): (i) supplying at least one medicine and at least one wax into an extruder which has a drum temperature and a mould temperature set higher than a melting point of at least one wax; and (ii) simultaneously melting and mixing at least one wax in the extruder to prepare the melted mixed medicine and wax, spraying the melted mixed medicine and wax into a gaseous medium having a temperature lower than the melting point of wax through a spraying nozzle immediately attached to the mould located at the top of the extruder drum, thereby granulating the mixture.
EFFECT: developing the method for preparing the medicine containing the wax matrix granules, including the wax matrix granules containing the medicine and having an average particle size ranging within 40 to 200 mcm.
20 cl, 16 ex, 2 tbl, 5 dwg
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