COMPLEX PILLS WITH BARIUM SULPHATE, OXYMETHYLURACIL AND METRONIDASOLE FOR DIAGNOSING AND TREATING BOWEL DISEASES Russian patent published in 2012 - IPC A61K31/513 A61K31/4164 A61K33/00 A61K47/30 A61K47/38 A61K9/28 A61K49/04 A61P1/00 A61P31/04 

Abstract RU 2443419 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a therapeutic diagnostic radiopaque agent in the form of pills. As active substances, the declared agent contains oxymethyluracil 0.25 g and metronidasole 0.25 g, as well as a mixture of barium sulphate for X-raying and potato starch in proportions 4:1 or 6:1. As core-coating excipients, the agent contains 5% alcohol-acetone solution of acetylphthalyl cellulose, 3% aqueous solution of Kollidon 90F, 10% low-molecular polyethylene in hexane and the biological adhesive 'Sulphacrylate'.

EFFECT: invention provides anti-inflammatory and antimicrobial action, uniform distribution in bowels, controlled prolonged release and specified time disintegration.

5 dwg, 6 ex

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RU 2 443 419 C1

Authors

Shikova Julija Vital'Evna

Likhoded Vitalij Alekseevich

Plechev Vladimir Vjacheslavovich

Elova Elena Vladimirovna

Plecheva Dina Vladimirovna

Shikov Nikolaj Artemovich

Dates

2012-02-27Published

2010-11-08Filed