ASSOCIATED INACTIVATED NEWCASTLE DISEASE, INFECTIOUS BRONCHITIS, EGG DROP SYNDROME 76, INFECTIOUS BURSAL DISEASE AND REOVIRUS TENOSYNOVITIS EMULSION VACCINE Russian patent published in 2012 - IPC A61K39/15 A61K39/17 A61K39/295 A61P31/12 

FIELD: medicine.

SUBSTANCE: vaccine contains an active substance and a target additive. As the active substance, the vaccine contains a mixture of an avirulent purified antigen material of La Sota strain of ND virus. of fam. Paramyxoviridae, subfam. Paramyxovirinae, gen. Avulavirus, serotype 1, of an arivulent purified antigen material of H-52 strain of IB virus, fam. Coronaviridae, gen. Coronavirus, serotype Massachusetts, of an arivulent purified antigen material of BISS No. 113 strain of EDS-76 of fam. Adenoviridae, gen. Aviadenovirus, serotype 3, collection of FGU VGNKI BISS No. 113 DEP, of an arivulent purified antigen material of K-58 strain or BG strain of IBD virus, of fam. Birnaviridae, gen. Avibirnavirus, collection of FGU VGNKI K-58 No.122-DEP or BG 102 DEP respectively, or of an avirulent purified antigen material of 1133 strain of RTV virus, fam. Reoviridae, gen. Orthoreovirus, collection of FGU VGNKI 1133 - DEP taken in proportions 0.5:2.0:0.5:1:1 respectively and in the amounts to provide protective immunogenic activity of each antigen in a body after a target preparation has been introduced. As the target additive, the vaccine contains the oil adjuvant Montanide ISA- 70 VG.

EFFECT: invention provides induction in vaccinated poultry of high antibody level to ND, IB, EDS-76, IBD and RTV agents in 28 days after application of the vaccine which appears to remain unchanged for 12 days and transovarially transmitted to offsprings.

8 cl, 6 tbl, 10 ex, 5 dwg