METHOD FOR PREDICTION OF CLINICAL OUTCOME OF PENETRATING KERATOPLASTY Russian patent published in 2012 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: method for corneal engraftment prediction involving the ELISA examination of lachrymal fluid for the preoperative content of interleukine-1-beta (IL-1β), differing by the fact that the content of IL-10 in lachrymal fluid is additionally evaluated that is followed by making the IL-1β to IL-10 relation, and if the derived value falls within 0.15-0.20, a favourable clinical outcome of the keratoplasty achieving a clear corneal engraftment, while the value of 0.35 or higher shows an unfavourable clinical outcome accompanied by opacity.

EFFECT: method provides the accurate prediction of the clinical outcome of the keratoplasty and developing corneal graft rejection that promotes higher clinical effectiveness and better clinical outcome of the disease.

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