METHOD FOR PREDICTION OF GRAFT VS HOST DISEASE FOLLOWING PENETRATING KERATOPLASTY Russian patent published in 2013 - IPC G01N33/53 

Abstract RU 2472160 C1

FIELD: medicine.

SUBSTANCE: for prediction of graft vs. host disease following penetrating keratoplasty, an excised recipient's cornea is analysed for the presence of human herpes virus-6 (HHV-6) DNA; simultaneously, blood serum is examined for a level of HHV-6 immunoglobulins G (IgG). If observing corneal HHV-6 DNA and the serum IgG level less than 0.3 mcg/l, developing graft vs. host disease is predicted.

EFFECT: well-timed prescription of antiviral drug preparations by an improved postoperative therapeutic management pathway in patients with a high risk of graft rejection.

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RU 2 472 160 C1

Authors

Slepova Ol'Ga Semenovna

Mironkova Elena Aleksandrovna

Makarov Pavel Vasil'Evich

Kugusheva Anna Ehduardovna

Demkin Vladimir Vital'Evich

Sadokhina Tat'Jana Sergeevna

Dates

2013-01-10Published

2011-11-11Filed