COMPOUNDS BOUND WITH BIR DOMAIN OF IAP Russian patent published in 2012 - IPC C07K5/06 A61K38/05 A61P35/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to a compound of formula I

and pharmaceutical compositions containing them and used for IAP-function modulation by inhibiting the binding of BIR-binding protein and BIR domain of IAP and for treating proliferative diseases such as cancer. What is also disclosed is a compound of formula I marked by a detectable tag and an affinity tag which is applicable as a probe for identifying the compounds bound with BIR domain of IAP.

EFFECT: preparing the compounds used for IAP-function modulation.

33 cl, 4 tbl, 1 ex