METHOD FOR XENON ANAESTHESIA IN CHILDREN Russian patent published in 2012 - IPC A61M16/10 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, specifically anaesthesiology and may be used for xenon anaesthesia in surgical interventions in children. That is ensured by initial semiclosed circuit anaesthesia by bolus inhalations of sevoflurane with a facepiece starting with the concentration of 8 vol. % at gas flow 6-8 l/min with pure oxygen flow for 5 minutes. After achieving the surgical stage of anaesthesia (III₁) and a bispectral index (BIS index) 45-50 units, puncture and catheterisation of a peripheral and central vein follow. Thereafter, atropine is introduced that is followed by myoplegia with esmeron and placement of a laryngeal mask airway or insertion of an endotracheal tube. Thereafter, the sevoflurane supply is stopped, and repeated semiclosed circuit oxygen denitrogenisation at gas flow 6-8 l/min for 3-4 minutes supported by artificial pulmonary ventilation replaced by a closed circuit procedure. The xenon saturation is enabled by no-oxygen gas flow 0.9 l/min. When the oxygen concentration in the circuit decreases to 40-50%, the oxygen supply is opened with gas flow 4 ml/kg of the maintained concentration within 30%, while xenon flow rate is decrease at first to 0.4 l/min, then gradually to 0.05 l/min. The operation is started at the relation of xenon: oxygen equal to 65-55% : 30%. After the operation is completed, the xenon supply is stopped, while the oxygen supply is increased to 1.5 l/min for 5 min. Residual xenon is removed to a xenon regeneration system, and a patient is extubated, and the laryngeal mask is removed.

EFFECT: method provides the optimal level of anaesthetic depth and safety in given category of patients with simultaneous increase in xenon and narcotic analgesic consumption, as well as improvement of anaesthetic quality and reliability.

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