OPHTHALMOLOGIC COMPOSITION WITH AMPHOTERIC SURFACE-ACTIVE SUBSTANCE HYALURONIC ACID Russian patent published in 2012 - IPC A61L12/08 A61L101/32 A61K9/08 A61P27/04 

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions relates to medicine, in particular, to ophthalmology. Ophthalmologic compositions contain from 0.1 ppm to 10 ppm of cationic antimicrobial component, selected from group, consisting of biguanides, polymer biguanides, quaternary ammonium compounds and any their mixture; 0.005-0.15 wt % of hyaluronic acid; and 0.01-1.0 wt % of amphoteric surface-active substance of formula I, where R¹ represents R or -(CH₂)_n-NHC(O)R, where R represents C₈-C₁₈ alkyl, which can be replaced by hydroxyl group and equals 2, 3 or 4; R² and R⁴ each is independently selected from methyl, ethyl, propyl or isopropyl; and R⁴ represents C₂-C₈ alkylene, which can be substituted by hydroxyl group.

EFFECT: invention ensures application of ophthalmologic compositions for purification and disinfection of contact lenses and, in particular, soft silicon hydrogel contact lenses.

12 cl, 15 tbl, 5 dwg, 5 ex