SALTS OF PYRROLOPYRIMIDINONE DERIVATIVES AND METHOD OF OBTAINING THEM Russian patent published in 2012 - IPC C07D487/04 C07D241/04 A61K31/517 A61P9/12 A61P11/00 A61P13/08 A61P15/10 

Abstract RU 2448967 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to novel acid-additive salts of pyrrolopyrimidinone derivative, represented by formula (1) which is selected from gentisate, maleate, citrate, fumarate and semitartrate salts, which possess improved properties in their application, in particular higher stability.

EFFECT: invention also relates to method of obtaining acid-additive salts of pyrrolopyrimidinone derivative, represented by formula (1) and to pharmaceutical composition, containing them, for treatment and prevention of erectile dysfunction, pulmonary arterial hypertension, chronic obstructive lung disease, benign prostate gland hypertrophy and diseases of lower urinary tract.

11 cl, 30 ex, 7 tbl

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RU 2 448 967 C2

Authors

Kim Dzae-Sun

Kim Nam Kho

Li Dzin Joung

Li Nam Kiu

Li Joon-Dzung

Dzang Voo Dzae

Joun Von-No

Okh Dzoon Gio

Sung Dzin-Kheung

Um Kej An

Dates

2012-04-27Published

2007-07-03Filed