Show metadata Hide metadata

(19)

(11)

2 449 790

(13)

(51)

IPC

A61K31/435(2006-01-01)

A61P25/16(2006-01-01)

(21) (22)

Application

2009138966/15, 2008-03-27

(24)

Start date

2008-03-27

(22)

Actual filing date

2008-03-27

(45)

Published

2012-05-10

(72)

Inventor

Bergman Dzhon E.Katshell Nejl S.Demopulos Gregori A.Florio Vinsent A.Gajtanaris DzhordzhGrej PatrikKhokhman DzhonOnrjust ReneZeng Khongkuj

(73)

Holder

Omeros Korporejshen

USING PDE7 INHIBITORS FOR TREATING MOVEMENT DISORDERS Russian patent published in 2012 - IPC A61K31/435 A61P25/16

Abstract RU 2449790 C2

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine. Namely neurology, and concerns using PDE7 inhibitors for treating movement disorders. For this purpose the PDE7 inhibitor is introduced as a single agent therapy or in a combination with a dopaminergic drug in therapeutically effective amounts.

EFFECT: invention provides effective treatment of movement disorders, particularly in Parkinson's disease, due to PDE7 ability to activate postsynaptic dopamine signal transmission in brain regions associated with movement.

66 cl, 7 ex, 6 tbl, 27 dwg

Similar patents RU2449790C2

Title	Year	Author	Number
USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS	2010	Bergmann John E. Cutshall Neil S. Demopulos Gregory A. Florio Vincent A. Gaitanaris George Gray Patrick Hohmann John Onrust Rene Zeng Hongkui	RU2600869C2
MEDICINAL PRODUCT APHANZOMENON FLOS AQUAE, EXTRACTS AND PURIFIED COMPONENTS OF EXTRACTIONS FOR TREATMENT OF NEUROLOGIC, NEURODEGENERATIVE AND AFFECTIVE DISORDERS	2007	Skol'O Stefano Kanestrari Franko Benedetti Serena Benedetti Janina Del'Gado-Ehsteban Marija	RU2441663C2
APPLICATION OF K-252A DERIVATIVES TO TREAT DISORDERS OF PERIPHERAL OR CENTRAL NERVOUS SYSTEMS AND EXCESSIVE CYTOKINE OUTPUT	1997	Ehngber Tomas M. Khaun Forrest A. Saporito Majkl S. Ehjmon Lajza D. Miller Mehtt'Ju S. Najt Ehrnest Ml.	RU2183959C2
THERAPEUTIC APPLICATION OF SELECTIVE INHIBITORS PDE10	2003	Lebel Lorrejn Ehnn Menniti Frank Sehm'Juehl' Shmidt Kristofer Dzhozef	RU2303259C2
POLYPEPTIDE WITH PHOSPHODIESTERASE ENZYMATIC ACTIVITY	1998	Lokni Kejt	RU2272841C2
SELECTIVE INVERSE SEROTONIN 2A/2C RECEPTOR AGONISTS APPLICABLES AS THERAPEUTIC AGENTS FOR NEURODEGENERATIVE DISORDERS	2008	Uehjner Dehvid M. Dehvis Robert E. Brehnn Mark R. Nehsh Norman Anderson Karl-Magnus A. Ul'Dam Alan K.	RU2465267C2
SELECTIVE SEROTONIN 2A/2C RECEPTOR INVERSE AGONISTS, USED AS THERAPEUTICS FOR NEURODEGENERATIVES DISEASES	2004	Uehjner Dehvid M. Dehvis Robert E. Brehnn Mark R.	RU2332401C2
PHOSPHODIESTERASE INHIBITORS APPLIED VIA THE TRANSVAGINAL ROUTE FOR THE TREATMENT OF INFERTILITY	2012	Pardina Palekha Marija Karmen Vas-Romero Unja Migel Ankhel	RU2601913C2
SUBSTITUTED 2-PHENYL-1-(3,4-DIHYDROXY-5-NITROPHENYL)-1-ETHANONES, METHOD FOR TREATMENT OF SOME DISTURBANCES IN CENTRAL AND PERIPHERAL NERVOUS SYSTEM AND PHARMACEUTICAL COMPOSITION CONTAINING INDICATED SUBSTANCES	1999	Benesh Jan Suarish Da Silva Patris'Ju Manuehl V'Ejra Arauzhu Lermont Dehvid Aleksander	RU2232748C2
3,5-DISUBSTITUTED PHENYL-PYPERIDINES AS DOPAMINE NEUROTRANSMISSION MODULATORS	2006	Sonesson Klas	RU2418787C2

RU 2 449 790 C2

Authors

Bergman Dzhon E.

Katshell Nejl S.

Demopulos Gregori A.

Florio Vinsent A.

Gajtanaris Dzhordzh

Grej Patrik

Khokhman Dzhon

Onrjust Rene

Zeng Khongkuj

Dates

2012-05-10—Published

2008-03-27—Filed