PYRIMIDYLAMINOBENZAMIDE DERIVATIVES FOR NEUROFIBROMATOSIS Russian patent published in 2012 - IPC A61K31/506 A61K31/502 A61K31/553 A61P35/00 A61P25/00

Abstract RU 2450814 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions refers to medicine, namely neurooncology and may be used for treating benign cerebral tumours. That is ensured by using 4-methyl-3-[[4 (3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl]benzamide and its N-oxide or pharmaceutically acceptable salt for preparing a pharmaceutical composition.

EFFECT: group of inventions allows treating benign cerebral tumours, particularly neurofibromatoses by means of inhibiting both signal pathways involving PDGFR and Kit receptors.

7 cl, 1 tbl, 2 ex

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RU 2 450 814 C2

Authors

Manli Pol U.

Dates

2012-05-20—Published

2006-12-05—Filed