FIELD: medicine, peptides, biochemistry. SUBSTANCE: invention relates to novel peptide agents eliciting immunostimulating activity. Invention proposes to use the novel synthetic peptide of structural formula: Trp-Thr-Ala-Glu-Glu-Arg-Gln-Leu as an agent with immunostimulating activity. Activity of peptide Trp-Thr-Ala-Glu-Glu-Arg-Gln-Leu is evident in 10-fold less doses as compared with prototype. Agent can be used in medicine for prophylaxis and treatment of patients with extended immunodeficient states of different etiology and designated for control of immunodeficiency. EFFECT: new peptide indicated above, broadened arsenal, enhanced biological activity. 6 tbl
Title | Year | Author | Number |
---|---|---|---|
PREPARATION STIMULATING THE DIFFERENTIATION OF T-LYMPHOCYTES | 2001 |
|
RU2188032C1 |
METHOD OF PREPARING SUBSTANCE ELICITING IMMUNOSTIMULATING ACTIVITY | 2000 |
|
RU2177325C1 |
AGENT STIMULATING FIBROBLAST PROLIFERATION | 2002 |
|
RU2211046C1 |
ANTIBODIES DIRECTED TO CD127 | 2015 |
|
RU2734076C2 |
METHODS FOR CELL CULTIVATION AND SETS AND DEVICE FOR THEM | 2016 |
|
RU2761557C2 |
ANTIBODIES TO BTN3A AND THEIR USE IN THE TREATMENT OF CANCER OR INFECTIOUS DISEASES | 2019 |
|
RU2800726C2 |
REAGENTS FOR REPRODUCTION OF CELLS EXPRESSING RECOMBINANT RECEPTORS | 2018 |
|
RU2783956C2 |
INTERLEUKIN 15 PROTEIN COMPLEX AND USE THEREOF | 2015 |
|
RU2711979C2 |
ANTIBODIES TO HUMAN INTERLEUKIN-2 AND THEIR APPLICATION | 2018 |
|
RU2745451C1 |
COMBINATION OF CELL THERAPY AND IMMUNOMODULATOR COMPOUND | 2018 |
|
RU2777911C2 |
Authors
Dates
2002-01-10—Published
2000-10-30—Filed