PEPTIDES SHOWING ANTISTRESS, ANTICONVULSANT AND NEUROPROTECTIVE EFFECT Russian patent published in 1998 - IPC

Abstract RU 2115660 C1

FIELD: chemistry of peptides. SUBSTANCE: product: peptides of the general formula: Trp-X-Gly-Gly-Asp-R where X - residue of hydroxyl-containing amino acid of L- or D-configuration; R - peptide Ala-Ser-Gly-Glu or Ala-Ser-Gly, or Ala-Ser or Ala, and their pharmaceutically acceptable salts also. Synthesis of peptides is carried out by the successive peptide chain splicing using tert.-butylhydroxycarbonyl scheme of solid-phase peptide synthesis. Synthesis is carried out at automatic regime in peptide synthesizer. Synthesized peptides are used in medicine since they show antistress, anticonvulsant and neuroprotective effect. EFFECT: improved method of synthesis, enhanced effectiveness of peptides. 7 tbl

Similar patents RU2115660C1

Title Year Author Number
USING DELTA SLEEP INDUCING PEPTIDE FOR HEPATOPROTECTIVE EFFECT IN CHRONIC IMMOBILISATION STRESS 2013
  • Belykh Andrej Evgen'Evich
  • Krjukov Aleksej Anatol'Evich
  • Bobyntsev Igor' Ivanovich
  • Shepeleva Ol'Ga Mikhajlovna
RU2538686C1
AGENT FOR DISEASES ASSOCIATED WITH STRESS-RELATED CONDITIONS IN DISEASES AND DISORDERS IN HUMAN AND ANIMALS, AND ALSO METHOD OF TREATING AND/OR PREVENTING WITH USING SUCH AGENT 2009
  • Mikhaleva Inehsa Ivanovna
  • Vojtenkov Vladislav Borisovich
  • Prudchenko Igor' Arkad'Evich
  • Ivanov Vadim Tikhonovich
RU2450823C2
USING DELTA-SLEEP INDUCING PEPTIDE FOR HEPATOPROTECTIVE ACTION IN CHRONIC EMOTIONAL PAIN STRESS 2013
  • Belykh Andrej Evgen'Evich
  • Krjukov Aleksej Anatol'Evich
  • Bobyntsev Igor' Ivanovich
  • Dudka Viktor Tarasovich
  • Smakhtin Mikhail Jur'Evich
  • Dolgintsev Maksim Evgen'Evich
  • Shepeleva Ol'Ga Mikhajlovna
  • Chernysheva Ol'Ga Igorevna
RU2537032C2
METHOD OF SYNTHESIS OF δ-SLEEP PEPTIDE 1995
  • Bezrukov M.V.
  • Panchenko A.E.
  • Prudchenko I.A.
  • Mikhaleva I.I.
  • Ivanov V.T.
RU2111972C1
METHOD OF PREPARING ENZYME DESTABILASE SHOWING FIBRINOLYTIC, THROMBOLYTIC, ENDO- AND EXO-GAMMA)-LYS-ISOPEPTIDASE AND AMIDOLYTIC ACTIVITY 1994
  • Sverdlov E.D.
  • Baskova I.P.
  • Zavalova L.L.
  • Luk'Janov S.A.
  • Barsova E.V.
  • Bogdanova E.A.
RU2112528C1
TOOLS FOR CORRECTING THE DESYNCHRONOSIS CAUSED BY A DISTURBANCE IN THE LIGHT REGIME 2017
  • Batotsyrenova Ekaterina Gennadevna
  • Gavrilenkova Lyudmila Pavlovna
  • Gadon Vladimir Lvovich
  • Ivanov Maksim Borisovich
  • Kashuro Vadim Anatolevich
  • Slyakotkin Nikolaj Vladimirovich
RU2660578C1
ANTISTRESS AND NOOTROPIC PREPARATION OF ANTIVIRAL AND IMMUNOSTIMULATING ACTION 2001
RU2211703C2
MEANS FOR THERAPY OF TOXIC ENCEPHALOPATHY CAUSED BY CARBON MONOXIDE 2015
  • Basharin Vadim Aleksandrovich
  • Gavrilenkova Lyudmila Pavlovna
  • Slyakotkin Nikolaj Vladimirovich
  • Gadon Vladimir Lvovich
  • Kulazhin Oleg Anatolevich
RU2669779C2
GLYCOPEPTIDE FULLERENE DERIVATIVE SHOWING ADJUVANT ACTIVITY 1997
  • Zhmak M.N.
  • Vol'Pina O.M.
  • Kuprijanova M.A.
  • Andronova T.M.
  • Makarov E.A.
  • Romanova V.S.
  • Parnes Z.N.
  • Vol'Pin M.E.
  • Ivanov V.T.
RU2124022C1
CYCLIC PEPTIDES WITH ANTISTRESS EFFECT AND STRUCTURE SIMILAR TO CORTICOTROPIN 2007
  • Navolotskaja Elena Vital'Evna
  • Vanina Vera Ivanovna
  • Lipkin Valerij Mikhajlovich
  • Kolobov Aleksandr Aleksandrovich
  • Kampe-Nemm Elena Arturovna
  • Orlov Sergej Nikolaevich
RU2330860C1

RU 2 115 660 C1

Authors

Mikhaleva I.I.

Prudchenko I.A.

Mendzheritskij A.M.

Vilkov G.A.

Dates

1998-07-20Published

1997-01-28Filed