FIELD: biotechnology.
SUBSTANCE: described is a group of inventions involving a method of producing aggregated oligonucleotides and a method of producing aggregated oligonucleotides packed into a virus-like particle. In one embodiment, the method of producing aggregated oligonucleotides involves steps of providing oligonucleotides, denaturation of oligonucleotides, aggregation of oligonucleotides and obtaining aggregated oligonucleotides.
EFFECT: invention extends the range of methods for producing aggregated oligonucleotides packed into a virus-like particle.
21 cl, 13 dwg, 3 tbl, 9 ex
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