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2 453 310

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IPC

A61K31/185(2006-01-01)

A61K33/06(2006-01-01)

A61K9/00(2006-01-01)

A61K9/20(2006-01-01)

A61K47/00(2006-01-01)

A61P25/00(2006-01-01)

(21) (22)

Application

2010150324/15, 2010-12-09

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Start date

2010-12-09

(22)

Actual filing date

2010-12-09

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Published

2012-06-20

(72)

Inventor

Sernov Lev NikolaevichKesarev Oleg GeorgievichSkachilova Sofija JakovlevnaPogorelyj Vasilij EfremovichOlejnikova Oksana NikolaevnaMakarova Larisa MikhajlovnaShilova Elena VladimirovnaMitrokhin Nikolaj MikhajlovichKesareva Zinaida AleksandrovnaBudunova Antonina PetrovnaShuleshkina Natalija Sergeevna

(73)

Holder

Otkrytoe Aktsionernoe Obshchestvo Nauchnyj Tsentr Po Bezopasnosti Biologicheski Aktivnykh Veshchestv" Bav")

AGENT POSSESSING NEUROPROTECTIVE ACTION IN ISCHEMIC CEREBRAL INJURY AND HYPOXIA, REPRESENTING MAGNESIUM 2-AMINOETHANESULFONATE, PHARMACEUTICAL COMPOSITIONS Russian patent published in 2012 - IPC A61K31/185 A61K33/06 A61K9/00 A61K9/20 A61K47/00 A61P25/00

Abstract RU 2453310 C1

FIELD: medicine.

SUBSTANCE: what is presented is a therapeutic agent possessing neuroprotective action in ischemic cerebral injury and hypoxia, representing magnesium 2-aminoethanesulfonate (magnesium taurinate). It has been shown that magnesium taurinate possesses high neuroprotective action; therapeutic application of magnesium 2-aminoethanesulfonate 50 mg/kg in cerebral ischemia caused by one-side occlusion of a left carotid, and prevents the developing ischemic cerebral injuries more effectively than if applying Picamilonum. There are also presented: solid dosage pharmaceutical composition on the basis of this compound in the form of tablets, capsules, powders, and a pharmaceutical composition for injections.

EFFECT: neuroprotective properties enable the presented pharmaceutical compositions of magnesium taurinate suggested to be used for preventing and treating ischemic cerebral injures.

6 cl, 4 tbl

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RU 2 453 310 C1

Authors

Sernov Lev Nikolaevich

Kesarev Oleg Georgievich

Skachilova Sofija Jakovlevna

Pogorelyj Vasilij Efremovich

Olejnikova Oksana Nikolaevna

Makarova Larisa Mikhajlovna

Shilova Elena Vladimirovna

Mitrokhin Nikolaj Mikhajlovich

Kesareva Zinaida Aleksandrovna

Budunova Antonina Petrovna

Shuleshkina Natalija Sergeevna

Dates

2012-06-20—Published

2010-12-09—Filed