STABLE CRYSTLALLINE FORM OF 2-ETHYL-6-METHYL-3-OXYPYRIDINE SUCCINATE AND SYNTHESIS METHOD THEREOF Russian patent published in 2012 - IPC C07D213/65 

Abstract RU 2453538 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a crystalline form of 2-ethyl-6-methyl-3-oxypyridine succinate which is stable during storage and a synthesis method thereof. Synthesis is carried out in water with molar ratio 2-ethyl-6-methyl-3-oxypyridine: succinic acid: water equal to (1:1.055-1.066:10-12) and the end product is extracted at temperature from 0 to +5°C.

EFFECT: stability of the obtained product during storage, absence of toxic impurities, method avoids use of toxic and inflammable organic solvents, which improves working conditions and prevents contamination of the environment and the working area.

7 cl, 21 ex, 9 dwg

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RU 2 453 538 C1

Authors

Germanov Sergej Borisovich

Gomzhin Andrej Mikhajlovich

Germanova Ol'Ga Leonidovna

Filippova Elizaveta Sergeevna

Missjul' Aleksandr Borisovich

Dates

2012-06-20Published

2011-04-06Filed