PHARMACEUTICAL COMPOSITION FOR INJECTIONS AND METHOD FOR ITS OBTAINING Russian patent published in 2013 - IPC A61K9/08 

Abstract RU 2491054 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to field of medicine and veterinary. Stable pharmaceutical composition for injections, contains water solution of 2-ethyl-6-methyl-3-oxypyridine succinate and auxiliary substance, and as auxiliary substance carbonic acid is applied, composition is obtained by mixing with the following component ratio (wt %): 2-ethyl-6-methyl-3-oxypyridine succinate 1-10; carbonic acid 0.01-0.5; water for injection to 100. Method of composition obtaining by i.1 is characterised by the fact, that filling and sealing ampoules on syringe filling machine is carried out in steam of carbonic acid, and sterilising filtration of 2-ethyl-6-methyl-3-oxypyridine succinate solution before filling is carried out under pressure of carbon dioxide.

EFFECT: pharmaceutical composition does not possess allergenic properties and is highly stable during entire normative storage term.

5 cl, 4 tbl, 8 ex

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RU 2 491 054 C1

Authors

Germanov Sergej Borisovich

Timko Vladimir Grigor'Evich

Gomzhin Andrej Mikhajlovich

Zykova Ol'Ga Valer'Evna

Dates

2013-08-27Published

2012-05-02Filed