ALICYCLIC COMPOUNDS, A METHOD OF THEIR SYNTHESIS, A PHARMACEUTICAL COMPOSITION SHOWING ANTI-INFLAMMATORY ACTIVITY AND A METHOD OF TREATMENT OF PATIENTS WITH INFLAMMATION Russian patent published in 1999 - IPC

FIELD: organic chemistry and technology, medicine. SUBSTANCE: invention relates to new alicyclic compounds of the general formula (I) where bonds between C₂ and C₃ and/or between C₄ and C₅ are the unsaturated ones; X means COOH, H, F, Br, J, COOR''; R means alkyl, arylalkyl, arylalkenyl group, free or protected aryl-group at condition that each of these groups has to contain 6-30 carbon atoms and R is not a group of the formula (II) ; aryl means phenyl, naphthyl or anthryl and if R is a substituted group then its substituents can be the following groups: C_1-12-alkylhydroxy, C_2-12-alkenylhydroxy, C_3-12-cycloalkyl, C_1-12-hydroxyalkyl or adamantyl; R' means H or C_1-6-alkyl; R'' means H, C_1-6-alkyl. Invention describes a method of synthesis of compounds of the formula (I) showing an anti-inflammatory activity and a method of treatment of patients with inflammations. EFFECT: improved method of synthesis, an anti-inflammatory activity of compounds. 13 cl, 5 tbl, 37 ex