FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing tamsulosin hydrochloride. The method involves reaction of R-5-(2-aminopropyl)-2-methoxybenzene sulphonamide molar excess of 1-(2-bromoethoxy)-2-ethoxybenzene which ranges from about 1.3 to about 3, in an organic solvent. Said organic solvent is methanol. The method further involves purification of the obtained tamsulosin hydrochloride by recrystallising tamsulosin hydrochloride from a solution in methanol or ethanol or from a mixture of ethanol and methanol. Recrystallisation is carried out from a mixture of methanol and ethanol in ratio from about 3:7 to about 7:3.
EFFECT: high optical purity of the desired tamsulosin hydrochloride.
5 cl, 7 ex
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