FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine and pharmacy and represents an immunostimulating extract of one or more bacterial strains Escherichia coli wherein the process of preparing the extract involves lysing one or more bacterial strains at pH more than 12 and processing the extract to separate nucleic acids, and wherein the extract: causes no risk of a prion disease when introduced into the patient, contains less than 100 mcg/ml of nucleic acid, contains chemically modified saccharides, including chemically modified lipopolysaccharide, and contains at least one amino acid which is specified in aspartic acid, glutamic acid, serine, histidine, alanine, arginine, tyrosine, methionine, phenylalanine and lysine; and it is racemised at least by 10%.
EFFECT: invention provides maximum safety and efficacy.
52 cl, 9 ex, 6 tbl, 7 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| BACTERIAL EXTRACT FOR RESPIRATORY DISORDERS AND METHOD FOR PREPARING IT | 2008 |
|
RU2456007C2 |
| IMMUNOMODULATORY EXTRACTS OF BACTERIA Lactobacillus AND METHODS FOR PREPARING AND USING THEM | 2008 |
|
RU2500412C2 |
| METHOD OF PRODUCING STABLE BACTERIAL EXTRACTS AND USE THEREOF AS PHARMACEUTICAL PREPARATIONS | 2020 |
|
RU2820605C2 |
| METHOD OF HUMAN RECOMBINANT TUMOR NECROSIS ALPHA-FACTOR PREPARING | 1997 |
|
RU2144958C1 |
| METHOD OF PRODUCING RECOMBINANT Β-1,4-GALACTOSIDASE BGAA FROM STREPTOCOCCUS PNEUMONIAE | 2019 |
|
RU2698460C1 |
| RECOMBINANT PLASMID pPA-OPRFI DNA CODING HYBRID RECOMBINANT F-I PROTEIN OF Pseudomonas aeruginosa OUTER MEMBRANE, STRAIN Escherichia coli PA-OPRFI PRODUCING HYBRID RECOMBINANT F-I PROTEIN OF Pseudomonas aeruginosa OUTER MEMBRANE AND METHOD FOR PRODUCING HYBRID RECOMBINANT F-I PROTEIN OF Pseudomonas aeruginosa OUTER MEMBRANE | 2011 |
|
RU2537006C2 |
| E. COLI STRAIN - PRODUCER OF ISOLATED DOMAIN 1 OF PROTECTIVE BACILLUS ANTHRACIS ANTIGEN IN FORM OF VIRUS-LIKE PARTICLES | 2016 |
|
RU2633508C1 |
| Ecoli BL21 (DE3)pLysS CELL STRAIN, pTT9/ASFVp30 CLONE CONTAINING RECOMBINANT PLASMID WITH INTEGRATION OF PART OF CP204L GENE OF AFRICAN SWINE FEVER VIRUS, ENCODING CONFORMATIONAL EPITOPE OF PROTEIN p30, FOR PRODUCING DIAGNOSTIC PREPARATIONS | 2011 |
|
RU2463343C1 |
| STRAIN Escherichia coli BL21(DE3)Gold/pETCYPopti - PRODUCER OF HUMAN RECOMBINANT CYCLOPHILIN A | 2015 |
|
RU2603283C1 |
| RECOMBINANT DNA ENCODING FUNCTIONALLY ACTIVE HYBRID PROTEIN OF D-AMINO ACID OXYDASE WITH CHITIN-COUPLING DOMAIN (DAOcbd), pVR1 RECOMBINANT PLASMID PROVIDING SYNTHESIS THEREOF IN Escherichia coli CELLS AND RECOMBINANT Escherichia coli STRAIN C 41 (DE3)/pVR1 AS PRODUCER OF DAOcbd | 2006 |
|
RU2310688C1 |
