FIELD: chemistry.
SUBSTANCE: polycrystalline silicon powder with mean grain size of about 5 mcm is put into a chemical etching solution consisting of a mixture of hydrofluoric and nitric acid and water in ratio 2:1:10, and held therein for 60-90 minutes while stirring continuously until the end of porosification of silicon. The powder of porous silicon is then filtered, dried for 30 minutes at temperature of about 100°C and mixed with a solution of a photosensitiser from the class of cyclic tetrapyrroles with concentration from 5×10-5 to 3×10-3 mol/l. The obtained suspension is filtered and dried on air.
EFFECT: obtaining a novel hybrid photosensitiser, which widens the range of agents for action on cancer cells through photodynamic therapy.
1 dwg, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| NANOCOMPOSITE PHOTOSENSITISER FOR METHOD OF PHOTODYNAMIC CELL EFFECT | 2006 |
|
RU2329061C1 |
| METHOD FOR PRODUCING CHLORINES AND PHARMACEUTICAL APPLICATIONS THEREOF | 2009 |
|
RU2513483C2 |
| PHOTOSENSIBILISER AND METHOD OF OBTAINING THEREOF | 2013 |
|
RU2535097C1 |
| ATROPISOMERS OF HALOGENATED TETRAPHENYLBACTERIOCHLORINS AND CHLORINS AND THEIR USE IN PHOTODYNAMIC THERAPY | 2016 |
|
RU2712266C2 |
| DRUG DELIVERY SYSTEM FOR ADMINISTERING HYDROPHOBIC MEDICAMENTS | 2002 |
|
RU2279872C2 |
| DERIVATIVES OF FLUORINE-CONTAINING CHLORINS EXHIBITING ANTI-TUMOUR ACTIVITY | 2019 |
|
RU2725876C1 |
| NOVEL PORPHYRIN DERIVATIVES, PARTICULARLY CHLORINS AND/OR BACTERIOCHLORINS AND USE THEREOF IN PHOTODYNAMIC THERAPY | 2005 |
|
RU2399622C2 |
| FLUORINATED PORPHYRIN DERIVATIVES EXHIBITING ANTI-TUMOR ACTIVITY | 2019 |
|
RU2707754C1 |
| METHOD FOR PREPARING 6β-FORMYL-B-NORCHOLESTANE-3β,5β-DIOL | 2005 |
|
RU2281289C1 |
| COMPOUND | 2002 |
|
RU2323940C2 |
