NANOCOMPOSITE PHOTOSENSITISER FOR METHOD OF PHOTODYNAMIC CELL EFFECT Russian patent published in 2008 - IPC A61K41/00 A61P35/00 C01B31/02 C01B33/02 

Abstract RU 2329061 C1

FIELD: medicine.

SUBSTANCE: invention can be used for photodynamic therapy method (PDT) of oncology diseases. As nanocomposite photosensitiser, powder consisting of porous silicon particles, including silicon crystals of sizes 2 to 4 nm with fullerene molecules adsorbed on crystal surface (e.g., C60 or C70) is offered, at relative fullerene in nanocomposite 0.3% to 4% by mass. The powder can be used in PTD, as, e.g. aqueous or saline suspension.

EFFECT: photosensitiser is high-effective to generate singlet oxygen, stable to water solutions aggregation, nontoxic for organism.

5 cl, 1 dwg

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RU 2 329 061 C1

Authors

Gurtov Valerij Alekseevich

Kuznetsov Sergej Nikolaevich

Pikulev Vitalij Borisovich

Saren Andrej Aleksandrovich

Dates

2008-07-20Published

2006-10-23Filed