FIELD: chemistry.
SUBSTANCE: described are novel 1,2,4-triazolones of general formula (I):
, where A denotes N and values of other radicals are given in the claim, which are vasopressin receptor inhibitors, synthesis method thereof and use thereof to prepare medicinal agents for treating and/or preventing diseases, particularly for treating and/or preventing cardiovascular diseases.
EFFECT: high efficiency of using said derivatives.
6 cl, 512 ex
| Title | Year | Author | Number |
|---|---|---|---|
| 4-(4-CYANO-2-THIOARYL)-DIHYDROPYRIMIDINONES AND USING THEM | 2008 |
|
RU2497813C2 |
| APPLICATION OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES | 2012 |
|
RU2638830C2 |
| NEW ACYCLIC, SUBSTITUTED FUROPYRIMIDINE DERIVATIVES AND THEIR APPLICATION FOR TREATING CARDIOVASCULAR DISEASES | 2006 |
|
RU2454419C2 |
| NEW ANTHELMINTIC QUINOLINE-3-CARBOXAMIDE DERIVATIVES | 2017 |
|
RU2772283C2 |
| PESTICIDE COMPOUNDS | 2018 |
|
RU2786724C2 |
| SUBSTITUTED CHROMANOL DERIVATIVES AND METHOD FOR PREPARING THEM | 2007 |
|
RU2459817C2 |
| CORTICOTROPIN-RELEASING FACTOR ANTAGONISTS | 1995 |
|
RU2221799C2 |
| METHOD OF RESIDUAL LIPOPROTEINS PRODUCING INHIBITION | 2004 |
|
RU2330682C2 |
| HERBICIDAL COMPOSITION CAPABLE OF PRODUCING SYNERGISTIC EFFECT AND METHOD FOR COMBATTING UNDESIRED WEED VEGETATION IN USEFUL VEGETATIONAL CULTURES | 1991 |
|
RU2041628C1 |
| AZOLIN COMPOUNDS, SUBSTITUTED WITH CONDENSED RING SYSTEM | 2015 |
|
RU2742767C2 |
