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2 460 724

(13)

(51)

IPC

C07D233/70(2006-01-01)

C07D249/12(2006-01-01)

C07D401/12(2006-01-01)

C07D403/12(2006-01-01)

C07D409/04(2006-01-01)

C07D409/14(2006-01-01)

A61K31/4166(2006-01-01)

A61K31/4178(2006-01-01)

A61K31/4196(2006-01-01)

A61P9/00(2006-01-01)

(21) (22)

Application

2008150598/04, 2007-05-21

(24)

Start date

2007-05-21

(22)

Actual filing date

2007-05-21

(45)

Published

2012-09-10

(72)

Inventor

Majer KhajnrikhBender EhkkhardBrjuggemajer Ul'FFlamme IngoKartkhaus DagmarKol'Kkhof PeterMajbom Daniehl'Shnajder DirkFeringer VerenaFjurstner Shantal'Kel'Denikh JorgLang DiterPook EhlizabetShmek Karsten

(73)

Holder

Bajer Shering Farma Aktsiengezel'Shaft

SUBSTITUTED ARYLIMIDAZOLONES AND TRIAZOLONES AS VASOPRESSIN RECEPTOR INHIBITORS Russian patent published in 2012 - IPC C07D233/70 C07D249/12 C07D401/12 C07D403/12 C07D409/04 C07D409/14 A61K31/4166 A61K31/4178 A61K31/4196 A61P9/00

Abstract RU 2460724 C2

FIELD: chemistry.

SUBSTANCE: described are novel 1,2,4-triazolones of general formula (I):

, where A denotes N and values of other radicals are given in the claim, which are vasopressin receptor inhibitors, synthesis method thereof and use thereof to prepare medicinal agents for treating and/or preventing diseases, particularly for treating and/or preventing cardiovascular diseases.

EFFECT: high efficiency of using said derivatives.

6 cl, 512 ex

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RU 2 460 724 C2

Authors

Majer Khajnrikh

Bender Ehkkhard

Brjuggemajer Ul'F

Flamme Ingo

Kartkhaus Dagmar

Kol'Kkhof Peter

Majbom Daniehl'

Shnajder Dirk

Feringer Verena

Fjurstner Shantal'

Kel'Denikh Jorg

Lang Diter

Pook Ehlizabet

Shmek Karsten

Dates

2012-09-10—Published

2007-05-21—Filed