DRUG FORM OF DISULFIRAM WITH PROLONGED ACTION AND METHOD OF ITS OBTAINING Russian patent published in 2012 - IPC A61K9/50 A61K31/145 A61P25/32 A61J3/00 

Abstract RU 2462235 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to field of medicine, namely to pharmaceutical industry and deals with disulfiram preparations. Medical form of disulfiram with prolonged action contains, at least, one microsphere from disulfiram, covered with first stabilising nanosize coating from neutral polysaccharides or gelatin, enclosed in second, spatially linked coating in form of microcapsule from neutral polysaccharides. Invention also deals with method of obtaining medical form of disulfiram with prolonged action.

EFFECT: application of claimed inventions ensures durative effect of prolonged action of disulfiram, stabile kinetics of drug release into tissues, sparing procedure of drug introduction and excludes possibility of its independent removal.

7 cl, 9 ex, 3 dwg

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RU 2 462 235 C1

Authors

Vilesov Aleksandr Dmitrievich

Galibin Oleg Vsevolodovich

Zvartau Ehdvin Ehduardovich

Krupitskij Evgenij Mikhajlovich

Panarin Evgenij Fedorovich

Tomson Vladimir Viktorovich

Belozertseva Irina Vladimirovna

Gen'Bach Ol'Ga Gennadievna

Dravolina Ol'Ga Andreevna

Suvorova Ol'Ga Mikhajlovna

Chukova Larisa Petrovna

Dates

2012-09-27Published

2011-05-10Filed