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(19)

(11)

2 463 303

(13)

(51)

IPC

C07D405/12(2006-01-01)

C07D405/14(2006-01-01)

C07D213/75(2006-01-01)

A61K31/5585(2006-01-01)

A61K31/4418(2006-01-01)

A61P11/00(2006-01-01)

(21) (22)

Application

2008122929/04, 2006-11-08

(24)

Start date

2006-11-08

(22)

Actual filing date

2006-11-08

(45)

Published

2012-10-10

(72)

Inventor

Adida Rua SaraKhehmilton Mehtt'JuMiller MarkGrotenkhejs Peter D. J.Bear BrajanMakkarti DzhejsonChzhou Tszinlan'

(73)

Holder

Verteks Farmas'Jutikalz Inkorporejted

HETEROCYCLIC MODULATORS OF ATP-BINDING CARTRIDGE TRANSPORTER Russian patent published in 2012 - IPC C07D405/12 C07D405/14 C07D213/75 A61K31/5585 A61K31/4418 A61P11/00

Abstract RU 2463303 C2

FIELD: medicine.

SUBSTANCE: invention refers to a new compound of formula or to its pharmaceutically acceptable salt. What is prepared and described is the new compound applicable as a modulator of ATP-binding cartridge (ABC) transporter or their fragments including a cystic fibrosis transmembrane regulator (CFTR).

EFFECT: higher efficacy.

1 cl, 422 ex, 7 tbl

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RU 2 463 303 C2

Authors

Adida Rua Sara

Khehmilton Mehtt'Ju

Miller Mark

Grotenkhejs Peter D. J.

Bear Brajan

Makkarti Dzhejson

Chzhou Tszinlan'

Dates

2012-10-10—Published

2006-11-08—Filed