EARLY DIAGNOSTIC TECHNIQUE FOR COMPLICATED SYSTEMIC INFLAMMATORY RESPONSE IN PATIENTS OPERATED IN BY-PASS ENVIRONMENT Russian patent published in 2012 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: there are measured clinical-laboratory criteria such as patient's body temperature more than 38°C or less than 36°C, heart rate more than 90 beats per minute, respiratory rate more than 20 per minute or hyperventilation PaCO₂≤32 mm Hg, blood leukocyte count more than 12×10⁹ /ml or less than 4×10⁹ /ml, the presence of immature granulocytes more than 10%. Patient's blood serum is additionally examined for the concentration of a soluble form of trigger receptor expressed on myelocytes (sTREM-1) in the preoperative (sTi) period and at any postoperative moment (sTpo) with the use of by-pass, while the development of complicated systemic inflammatory response is diagnosed by the increment rate sTREM-1≥1.5 calculated by formula K=sTpo/ sTi.

EFFECT: use of the technique enables higher accuracy of preclinical diagnosing and prediction of developing postoperative complicated systemic inflammatory response in the patients underwent cardiovascular bypass-assisted surgeries.

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